It makes most sense when you're chasing terabytes per pound and the NAS sits somewhere noise doesn't matter. Think garage, or a rack in the cupboard under the stairs. You also get five years' warranty, two more than the cheapest NAS lines. It's CMR, which is what you want anywhere near a RAID or ZFS rebuild.
!Watch out for
It's a 7,200 rpm drive and you'll hear it working.
Backblaze doesn't run enough of these for a failure rate we'd publish. Power draw is 4.14 W idle and 7.97 W working on Toshiba's figures, or 36 kWh a year if it spends the whole year idling. Put four in RAID 5 and you'll have 18 TB to fill (Windows will call it 16.4 TB).
Specifications
Each value links to the Toshiba page or datasheet it came from.